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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
21.82
Human Site:
S112
Identified Species:
30
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S112
Q
V
E
V
E
P
L
S
A
D
D
W
E
I
L
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S112
Q
V
E
V
E
P
L
S
A
D
D
W
E
I
L
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S112
Q
V
E
V
E
P
L
S
A
D
D
W
E
I
L
Dog
Lupus familis
XP_532459
1267
140567
E107
V
V
S
C
Q
Q
V
E
V
E
P
L
S
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S112
Q
V
E
V
E
P
L
S
A
D
D
W
E
I
L
Rat
Rattus norvegicus
P46462
806
89330
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
D99
W
V
E
G
R
S
G
D
H
D
E
N
V
V
E
Chicken
Gallus gallus
XP_418655
1290
143066
S112
Q
V
E
V
E
P
L
S
A
D
D
W
E
I
L
Frog
Xenopus laevis
P23787
805
89193
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
Honey Bee
Apis mellifera
XP_397107
1069
120490
L25
A
Y
L
P
D
T
W
L
R
K
L
E
T
K
E
Nematode Worm
Caenorhab. elegans
P54812
810
89622
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
S108
K
V
T
V
E
P
A
S
V
D
D
W
E
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
G151
T
V
F
V
N
L
D
G
E
L
A
K
R
L
E
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
100
6.6
N.A.
100
0
N.A.
20
100
0
0
N.A.
0
0
0
73.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
0
N.A.
33.3
100
0
0
N.A.
0
6.6
0
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
6
0
30
0
6
0
0
6
0
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
0
6
6
0
42
36
0
0
0
6
% D
% Glu:
0
0
36
0
36
0
0
6
6
6
6
6
36
0
18
% E
% Phe:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
6
6
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
36
0
% I
% Lys:
6
0
0
0
0
0
0
0
0
6
0
6
0
6
0
% K
% Leu:
0
0
6
0
0
6
30
6
0
6
6
6
0
6
36
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
6
0
0
0
0
0
0
6
0
0
0
% N
% Pro:
0
0
0
6
0
36
0
0
0
0
6
0
0
0
0
% P
% Gln:
30
0
0
0
6
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
6
0
0
0
6
0
0
0
6
0
0
% R
% Ser:
0
0
6
0
0
6
0
36
0
0
0
0
6
0
0
% S
% Thr:
6
0
6
0
0
6
0
0
0
0
0
0
6
0
0
% T
% Val:
6
53
0
42
0
0
6
0
12
0
0
0
6
6
0
% V
% Trp:
6
0
0
0
0
0
6
0
0
0
0
36
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _